Metyrapone
Overview
Metyrapone is inhibitor of 11b-hydroxylase, an important cytochrome P450 enzyme involved in the biosynthesis of cortisol and alsosterone. Metyrapone is administered orally. Metyrapone is used in the treatment of cushing's syndrome. Metyrapone is also used in tests of pituitary gland function..
Categories
- 18 Hormones and other endocrine drugs and contraceptives
Primary Characterstics
Indications
Back to top
Pharmacokinetics
Back to top
Contraindications
Back to top
Drug Interactions
No data regarding the interactions of Metyrapone was found.
Back to top
Side Effects
Back to top
Dosage
Metyrapone's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 750 mg | 750 (750) | 4 hourly | PO | For 6 doses |
Paedriatic Dosage (20kg)
|
| 15 mg/kg | 15 (15) | 4 hourly | Oral | 6 divided doses |
Neonatal Dosage (3kg)
|
| 15 mg/kg | 15 (15) | 4 hourly | Oral | For One Day |
High Risk Groups
Back to top
Warning / Precautions
Back to top
Storage Conditions
Back to top
Interference in Pathology
Back to top
Brands / Trade Names of
Metyrapone
Back to top
Previous Drug Generic - Next Drug Generic