Nystatin
Overview
Nystatin is antifungal agent obtained from Streotomyces noursei. It was one of the first polyene antibiotic of undetermined structure, discovered and used clinicaly. It acts as a fungistatic and fungicidal and active against most Candida species. Nystatin is a mixture of four different tetranes, primarily it A1, along with two other tetranes A2 or A3 and polyfungin B. Nystatin is very toxic for parentral administration and is only used topically.
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Nystatin's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 100000 to 600000 IU | 350000 (350000) | 24 hourly | Buccal | Preferably 2-4 times a day. |
Paedriatic Dosage (20kg)
|
| 100000 IU/gm | 100000 (100000) | 8 hourly | Buccal | - |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Nystatin is available. |
High Risk Groups
Drug should not be given to Pregnant Mothers, and Neonates.
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Nystatin
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