Sulphinpyrazone
Overview
Sulphinpyrazone is a sulfoxide analogue of phenylbutazone. Sulphinpyrazone is used as an uricosuric agent. Sulphinpyrazone is organic acid and act at the anionic transport sites of the renal tubule. Sulphinpyrazone is employed to decrease the body pool of urate in patients with tophaceous gout or in those with frequent gouty attacks. Sulphinpyrazone is not used for acute attacks of gout. It has been studied as an antithrombotic agent.
Categories
- 2 Analgesics, antipyretics, NSAIDs, antigout, and antirheumatics
Primary Characterstics
Indications
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Pharmacokinetics
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Side Effects
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Dosage
Sulphinpyrazone's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 0.48 to 0.95 mg/kg | 0.72 (0.715) | 8 hourly | PO | Initially for 2-3 Weeks |
| 2.86 to 3.81 mg/kg | 3.3 (3.335) | 8 hourly | PO | Maintenance |
Paedriatic Dosage (20kg)
|
| No data regarding the Paedriatic dosage details of Sulphinpyrazone is available. |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Sulphinpyrazone is available. |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Sulphinpyrazone
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Manufacturers of
Sulphinpyrazone
in Pakistan
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