Tolbutamide
Overview
Tolbutamide is a sulfonylurea compound. Tolbutamide is oral anti-diabetic agent, acts by increasing pancreatic insulin secretion. Tolbutamide is used in the treatment of non-insulin dependent diabetes. Tolbutamide is recommended when there is great danger of hypoglycemia (in elderly).
Categories
- 18 Hormones and other endocrine drugs and contraceptives
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Tolbutamide's dosage details are as follows:
Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
2.38 to 9.52 mg/kg | 6 (5.95) | 8 hourly | PO | - |
Paedriatic Dosage (20kg)
|
| | | | Not recommended in this age group |
Neonatal Dosage (3kg)
|
| | | | Not recommended in this age group |
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Tolbutamide
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