Tolbutamide

Overview

Tolbutamide is a sulfonylurea compound. Tolbutamide is oral anti-diabetic agent, acts by increasing pancreatic insulin secretion. Tolbutamide is used in the treatment of non-insulin dependent diabetes. Tolbutamide is recommended when there is great danger of hypoglycemia (in elderly).

Categories

Primary Characterstics

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Tolbutamide's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

2.38 to 9.52 mg/kg6 (5.95)8 hourlyPO-

Paedriatic Dosage (20kg)

Not recommended in this age group

Neonatal Dosage (3kg)

Not recommended in this age group

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Tolbutamide

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Manufacturers of Tolbutamide in Pakistan

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