Piretanide

Overview

Piretanide is a loop diuretic with actions, uses and adverse effects similar to those of frusemide. Piretanide is used in the management of mild to moderate hypertension associated with edema.

Categories

Primary Characterstics

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

The severe or irreversible adverse effects of Piretanide, which give rise to further complications include Urinary retention, Hyponatremia, Thrombocytopenia, Ototoxicity, Orthostatic hypotension, Leucopenia, Dehydration, Gout.

Piretanide produces potentially life-threatening effects which include Cardiac arrhythmia, Hypotension, Renal failure, Increased renal excretion of Ca, K, Mg. which are responsible for the discontinuation of Piretanide therapy.

The signs and symptoms that are produced after the acute overdosage of Piretanide include Dehydration, Hypovolemia, Delirium, Decreased sodium and water.

The symptomatic adverse reactions produced by Piretanide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Diarrhea, Urticaria, Erythema, Itching, Digestive disturbances.

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Dosage

Piretanide's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

6 to 24 mg/day15 (15)As recommended.PO

Paedriatic Dosage (20kg)

No data regarding the Paedriatic dosage details of Piretanide is available.

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Piretanide is available.

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Piretanide

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Manufacturers of Piretanide in Pakistan

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