Famotidine

Overview

Famotidine was introduced in mid 1970s. Famotidine is a histamine H2 receptor blocker and inhibits secretion of gastric acid produced by histamine. itused to treat and prevent duodenal and peptic ulcers, zollinger-ellison syndrome (hypersecretion of HCl) to treat gastroesophageal reflux disorder (heart burn).

Primary Characterstics

Indications

Pharmacokinetics

Contraindications

Drug Interactions

Famotidine is known to interact with other drugs, the details of drug interactions is as follows:

Severity N/A

Magnesium Trisilicate

Interaction of Magnesium Trisilicate with Famotidine

Details: Bioavailability of Famotidine is decreased when administered with antacids (e.g Magnesium Trisilicate)

Probenecid

Interaction of Probenecid with Famotidine

Details: Probenecid Increases Plasma Concentration of Famotidine

Ketoconazole

Interaction of Ketoconazole with Famotidine

Details: Absorption of Ketoconazole is reduced when administerd with famotidine

Alcohol

Interaction of Alcohol with Famotidine

Details: Level of ethanol is increased

Sodium Diatrizoate

Interaction of Sodium Diatrizoate with Famotidine

Details: Should not be use concurrently without informing doctor.

Ceftibuten

Interaction of Ceftibuten with Famotidine

These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Dosage

Famotidine's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
20 mg	20 (20)	12 hourly	IV
20 to 40 mg	30 (30)	24 hourly	PO	At bedtime.
Paedriatic Dosage (20kg)
				Safety not established
Neonatal Dosage (3kg)
				Safety not established

High Risk Groups

Warning / Precautions

Storage Conditions

Interference in Pathology

Brands / Trade Names of Famotidine

Manufacturers of Famotidine in Pakistan

Adfa Akson Al-Habib Albro Alina Alliance Alson Amass Ambrosia Amson Ardin Aries Atco Barrett Batala Benson Bex Bio Pharma Biogen Bloom Bosch Bryon Candid Caraway CARE PHARMA Caylex Cherwel Cibex Cirin Crest Danas Davis Delta Delux Don valley Dosaco Dr.Raza Drug Pharma Drugs E Pharm Efroze Elko English Epoch Euro Europak Evergreen F.M Fassgen Fedro Ferozson Ferroza Flow Fozan Friends Fynk Genera Genome Glitz Global Goodman L Gray's GSK Hamaz Hansel Harmann Heal Helicon Helix High-Q Highnoon Himont Pharma Hizat Honig Hygeia Ideal Innvotek Irza Jaens Jawa Jinnah Lawrence Lexicon Lotus Lowitt Mac & Rans Macquins Makson Mass Max Medera Mediceena Medicraft Medimpex Medisearch Medisure Meditech Mega Pharma Merck Miracle Muller Navegal Nawan Labs Nenza Neo Neutro Novamed Novartis Novins Obs Olive Labs Orta Pakheim Panacea Paramount PDH Pearl Pharmacare Pharmix Platinum Polyfine PPP Pulse Qintar Qureshi R.Y Raazee Rakaposhi Rasco Regent Reko Remington Robins Roryan Pharma Rotex Royal Consumer Saaaf Saffron Saydon Scotmann Semos Shafaz Shaheen Shaigan Shawan Shrooq Silver Siza Star Swiss Pharma Sycom Tabros Tagma TFC PHARMA TG Trigon Umersons Unipharma Usawa Valor Vega Venture Vital Webrose Werrick Wilshire Wilsons Wise Xenon Z-Jans Zafa Zanctok Zephyr Zinta

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