Clavulanic Acid
Overview
Clavulanic Acid is a ß lactamase inhibitor. Clavulanic Acid is structurally related to the penicillins and used in combination with penicillin antibiotic to treat variety of bacterial infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Clavulanic Acid is important to take the drug for the full time period as prescribed. If you discontinue the therapy it may result in ineffective treatment.
Categories
- 6 Anti-infective drugs
- 6.2 Antibiotics, systemic
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 125 mg | 120 (125) | 12 hourly | PO | Only in combination with either Amoxicillin or Ticarcillin. |
Paedriatic Dosage (20kg)
|
| No data regarding the Paedriatic dosage details of is available. |
Neonatal Dosage (3kg)
|
| 6 mg/kg | 6 (6) | 6 hourly | Intramuscular | |
| 6 mg/kg | 6 (6) | 6 hourly | Intravenous | |
| 6 mg.kg | 6 (6) | 6 hourly | oral | |
High Risk Groups
Drug should not be given to Pregnant Mothers.
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
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Warning / Precautions
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Storage Conditions
Inj (reconstituted susp)
Store in refrigerator. Use within 10 days if kept at room temperature.
Tab, Oral Susp, Dry Powder for Inj
Store at room temperature, Below 25°C. Protect from Moisture.
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Interference in Pathology
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Brands / Trade Names of
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Manufacturers of
Clavulanic Acid
in Pakistan
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